Professor David E Neal
David currently works as Senior Vice President for Global Research at Elsevier / RELX. He is Professor Emeritus at the Universities of Cambridge and Oxford.
In his role at Elsevier, he leads the Research Collaboration Unit, and provides perspective as a senior researcher and clinician on the provision of better informatic tools and data for researchers and clinicians; and in developing stronger partnerships with academia and industry. He also works on digital health solutions & clinical decision-support tools (https://researchcollaborations.elsevier.com/en/organisations/research-collaboration-unit). He is responsible for the International Centre for the Study of Research (ICSR) in Elsevier (https://www.elsevier.com/icsr), which works on better ways of measuring the social impact of research and research evaluation.
He has more than 38 years of academic experience and was Director of Research at a Russell Group University. He has domain expertise in clinical and translational studies of urological cancers; molecular abnormalities of androgen receptor signalling and gene alterations in prostate cancer; and in the clinical and surgical treatment of patients with urological cancers.
David is Fellow of the Academy of Medical Sciences 1998; Fellow of European Academy of Cancer Sciences, 2009; Fellow of Royal Society of Biologists, 2009; Senior Investigator of National Institute of Health Research, 2008; Honorary Fellow of the Faculty of Pharmaceutical Medicine 2008 and Fellow of the Roayl College of Surgeons of Edinburgh (ad hominem; Hunterian Professorship 1981; FRCS 1980; MB BS 1975; BSc(1sT) 1972 (UCL London). He has over £60 M of research funding including CRUK, NIHR, MRC. His publications have an “H” index of 104, and have been cited ~ 40,000 times. He has published over 800 papers, chapters and books.
David’s outside interests include playing classical guitar, cricket, jazz, vintage British motorcycles and listening to music.
Select publications
- Tran MGB, Bibby BAS, Yang L, Lo F, Warren AY, Shukla D,… & Neal DE. Independence of HIF1a and androgen signaling pathways in prostate cancer. BMC cancer. 2020;20(1):469.
- Neal DE, Metcalfe C, Donovan JL, Lane JA, Davis M, Young GJ, et al. Ten-year Mortality, Disease Progression, and Treatment-related Side Effects in Men with Localised Prostate Cancer from the ProtecT Randomised Controlled Trial According to Treatment Received. Eur. Urol. 2020;77(3):320-30.
- Warren AY, Massie CE, Watt K, Luko K, Orafidiya F, Selth LA, … Neal DE & Asim M. A reciprocal feedback between the PDZ binding kinase and androgen receptor drives prostate cancer. Oncogene. 2019;38(7):1136-50.
- Donovan JL, Opmeer B, Young GJ, Mills N, Martin RM, Lane JA, ….Neal DE & Hamdy FC. Factors associated with trial recruitment, preferences, and treatments received were elucidated in a comprehensive cohort study. Journal of clinical epidemiology. 2019;113:200-13.
- Wedge DC, Gundem G, Mitchell T, …… …. Neal DE, Cooper CS, Eeles RA. Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets. Nature genetics. 2018;50(5):682-92.
- Martin RM, Donovan JL, Turner EL, ………………. Neal DE, Hamdy FC. Effect of a Low-Intensity PSA-Based Screening Intervention on Prostate Cancer Mortality: The CAP Randomized Clinical Trial. JAMA. 2018;319(9):883-95.
- Hamdy FC, Donovan JL, Lane JA, ……… Neal DE. 10-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Localized Prostate Cancer. The New England journal of medicine. 2016;375(15):1415-24.
- Cooper CS, Eeles R, Wedge DC, …………. Neal DE. Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue. Nature genetics. 2015;47(4):367-72.
Select awards
- David was appointed CBE in the 2014 Queen’s New Year’s Honours List and was awarded the St Peter’s Medal for a major lifetime contribution from the British Association of Urological Surgeons
- He also has been awarded several medals from the Royal College of Surgeons of England and the BMA (Moynihan, Victor Horsley, Zachary Cope)