Annemieke ter Telgte, PhD
Annemieke ter Telgte, PhD, is senior postdoc at VASCage GmbH in Innsbruck, Austria. She received her PhD from the Department of Neurology at Radboudumc, Radboud University, Nijmegen, the Netherlands. Her research focuses on cerebral small vessel disease, particularly small acute brain infarcts (termed incidental DWI-positive lesions) and cerebral microinfarcts. During her PhD, she established the RUN DMC – InTENse study, a high-frequent serial MRI study on small acute brain infarcts in patients with cerebral small vessel disease. Subsequently, as a visiting researcher at Massachusetts General Hospital in Boston, she studied small acute brain infarcts microscopically. Her current work focuses on determining the risk factors and the clinical significance of small acute brain infarcts, studied in UK Biobank as well as through a pooled analysis of individual participant data. As Visiting Researcher at the University of Cambridge, she will conduct a secondary analysis of the PRESERVE trial to determine whether intensive blood pressure treatment is associated with a reduction in the combined outcome of incident brain infarcts on MRI and recurrent stroke, to explore the potential of this combined outcome as a surrogate endpoint for future clinical trials. Outside of her research, Annemieke loves swing dancing, being in nature, and spending time with friends and family.
Select publications
- ter Telgte A, de Kort AM, Dewenter A, Kopczak A, Gesierich B, Kuiperij HB, Klijn CJM, Duering M, Verbeek MM, Schreuder FHBM. Incidental DWI-Positive Lesions in 2 Cohorts of CAA and CADASIL: Prevalence, Distribution, and Associations With Clinical Variables. Neurology. 2026 Jul 28;107(2):e218160. doi: 10.1212/WNL.0000000000218160.
- ter Telgte A, Jouvent E. A New Era for Cerebral Small Vessel Disease: From Prevention of Stroke to Prevention of Small Brain Infarcts on Imaging. Neurology. 2024 Sep 10;103(5):e209837. doi: 10.1212/WNL.0000000000209837.
- ter Telgte A, Duering M. Cerebral Small Vessel Disease: Advancing Knowledge With Neuroimaging. Stroke. 2024 Jun;55(6):1686-1688. doi: 10.1161/STROKEAHA.123.044294.
- Duering M, Biessels GJ, Brodtmann A, Chen C, Cordonnier C, de Leeuw FE, Debette S, Frayne R, Jouvent E, Rost NS, ter Telgte A, Al-Shahi Salman R, Backes WH, Bae HJ, Brown R, Chabriat H, De Luca A, deCarli C, Dewenter A, Doubal FN, Ewers M, Field TS, Ganesh A, Greenberg S, Helmer KG, Hilal S, Jochems ACC, Jokinen H, Kuijf H, Lam BYK, Lebenberg J, MacIntosh BJ, Maillard P, Mok VCT, Pantoni L, Rudilosso S, Satizabal CL, Schirmer MD, Schmidt R, Smith C, Staals J, Thrippleton MJ, van Veluw SJ, Vemuri P, Wang Y, Werring D, Zedde M, Akinyemi RO, Del Brutto OH, Markus HS, Zhu YC, Smith EE, Dichgans M, Wardlaw JM. Neuroimaging standards for research into small vessel disease-advances since 2013. Lancet Neurology. 2023 May 23:S1474-4422(23)00131-X. doi: 10.1016/S1474-4422(23)00131-X.
- ter Telgte A, Scherlek AA, Reijmer YD, van der Kouwe AJ, van Harten T, Duering M, Bacskai BJ, de Leeuw FE, Frosch MP, Greenberg SM, van Veluw SJ. Histopathology of diffusion-weighted imaging-positive lesions in cerebral amyloid angiopathy. Acta Neuropathol. 2020 May;139(5):799-812. doi:10.1007/s00401-020-02140-y.
- ter Telgte A, Wiegertjes K, Gesierich B, Baskaran BS, Marques JP, Kuijf HJ, Norris DG, Tuladhar AM, Duering M, de Leeuw FE. Temporal Dynamics of Cortical Microinfarcts in Cerebral Small Vessel Disease. JAMA Neurol. 2020 May 1;77(5):643-647. doi: 10.1001/jamaneurol.2019.5106.
- ter Telgte A, Wiegertjes K, Gesierich B, Marques JP, Huebner M, de Klerk JJ, Schreuder FHBM, Araque Caballero MA, Kuijf HJ, Norris DG, Klijn CJM, Dichgans M, Tuladhar AM, Duering M, de Leeuw FE. Contribution of acute infarcts to cerebral small vessel disease progression. Ann Neurol. 2019 Oct;86(4):582-592. doi:10.1002/ana.25556.
- ter Telgte A, van Leijsen EMC, Wiegertjes K, Klijn CJM, Tuladhar AM, de Leeuw FE. Cerebral small vessel disease: from a focal to a global perspective. Nat Rev Neurol. 2018 Jul;14(7):387-398. doi: 10.1038/s41582-018-0014-y.
*shared first authorship
Select awards
- Bayer Thrombosis Research Award 2025
- Grant Recipient FWF Early Stage Programme: Research, Innovation and Training (ESPRIT). Grant DOI 10.55776/ESP505
