Professor Li Su
Professor Li Su is the head of the Artificial Intelligence and Computational Neuroscience Group, and has a joint appointment as Professor (Grade 12) in the Department of Psychiatry at the University of Cambridge and Sheffield Institute of Translational Neuroscience at the University of Sheffield.
Spanning over two universities, he leads a multi-disciplinary research group with members from Neuroscience, Psychology, Medical, Mathematics and Computer Science backgrounds. His research aims to combine innovative and original computational methods with the state-of-the-art brain imaging techniques (MEG/EEG, 7T MRI and PET) in understanding, detecting and developing treatments for neurological and psychiatric conditions. He is a Specialist Committee Member at National Institute for Health and Care Excellence (NICE), an Associate Editor for Frontiers in Computational Neuroscience and a member of Alzheimer’s Society’s Research Strategy Council.
Professor Su has published several high impact papers, many of which have been widely cited and made a real impact on the field. Professor Su has been awarded several grants and fellowships including a prestigious Senior Fellowship from Alzheimer’s Research UK.
Select publications
- Francesca R Farina, Katie Bridgeman, Sarah Gregory, Lucia Crivelli, Isabelle F Foote, Otto-Emil I Jutila, Ludmila Kucikova, Luciano I Mariano, Kim-Huong Nguyen, Tony Thayanandan, Funmi Akindejoye, Joe Butler, Ismael L Calandri, Giedrė Čepukaitytė, Scott T Chiesa, Walter D Dawson, Kay Deckers, Vanessa De la Cruz-Góngora, Maria-Eleni Dounavi, Ishtar Govia, Edmarie Guzmán-Vélez, Shimaa A Heikal, Tanisha G Hill-Jarrett, Agustin Ibanez, Bryan D James, Eimear McGlinchey, Donncha S Mullin, Graciela Muniz-Terrera, Maritza Pintado Caipa, Esraa M Qansuwa, Louise Robinson, Antonella Santuccione Chadha, Oliver M Shannon, Li Su, Wendy Weidner, Laura Booi (2024) Next generation brain health: transforming global research and public health to promote dementia prevention and risk reduction in young adult populations, Lancet Healthy Longevity. 5(12):100665
- Anna McKeever, Peter Swann, Maura Malpetti, Paul C Donaghy, Alan Thomas, Elijah Mak, Stephen F Carter, Jerry Tan, Young T Hong, Tim D Fryer, Amanda Heslegrave, Henrik Zetterberg, Li Su, Leonidas Chouliaras, James B Rowe, John T O’Brien (2024) Polygenic risk discriminates Lewy body dementia from Alzheimer’s disease, Alzheimer’s and Dementia. 21(2):e14381
- Audrey Low, Elizabeth McKiernan, Maria A. Prats-Sedano, Stephen F. Carter, James D. Stefaniak, Li Su, Maria-Eleni Dounavi, Graciela Muniz-Terrera, Natalie Jenkins, William Stewart, Katie Bridgeman, Karen Ritchie, Brian Lawlor, Lorina Naci, Paresh Malhotra, Clare Mackay, Ivan Koychev, Tony Thayanandan, Vanessa Raymont, Craig W. Ritchie, John T. O’Brien and PREVENT investigators (2024) Neuroimaging and Clinical Findings in Healthy Middle-Aged Adults with Mild Traumatic Brain Injury, JAMA Network Open, 7(8):e2426774
- Coco Newton, Marianna Pope, Catarina Rua, Richard Henson, Zilong Ji, Neil Burgess, Christopher T. Rodgers, Matthias Stangl, Maria-Eleni Dounavi, Andrea Castegnaro, Ivan Koychev, Paresh Malhotra, Thomas Wolbers, Karen Ritchie, Craig W. Ritchie, John O’Brien, Li Su, Dennis Chan; for the PREVENT Dementia Research Programme, (2024) Entorhinal-based path integration selectively predicts midlife risk of Alzheimer’s disease, Alzheimer’s and Dementia, 20(4):2779-2793
- Mehraram R, Peraza LR, Murphy NRE, Cromarty RA, Graziadio S, O’Brien JT, Killen A, Colloby SJ, Firbank M, Su L, Collerton D, Taylor JP, Kaiser M, (2022) Functional and Structural Brain Network Correlates of Visual Hallucinations in Lewy Body Dementia, Brain, 145(6): 2190–2205
- Leonidas Chouliaras, Alan J. Thomas, Maura Malpetti, Paul C. Donaghy, Joseph P.M. Kane, Elijah Mak, George Savulich, Maria Prats-Sedano, Amanda Heslegrave, Henrik Zetterberg, Li Su, James Rowe, John O’Brien (2021) Differential levels of plasma biomarkers of neurodegeneration in Lewy body dementia, Alzheimer’s disease, frontotemporal dementia and progressive supranuclear palsy, Journal of Neurology, Neurosurgery, and Psychiatry, 93(6):651-658. doi: 10.1136/jnnp-2021-327788.
- Relationship between tau, neuroinflammation and atrophy in Alzheimer’s disease: the NIMROD study. Su L, Surendranathan A, Huang Y, Bevan-Jones WR, Passamonti L, Hong YT, Arnold R, Vázquez Rodríguez P, Wang Y, Mak E, Fryer TD, Aigbirhio F, Rowe JB, O’Brien JT, Information Fusion, 67: 116-124. (2021)
- Microglial activation and tau burden predict cognitive decline in Alzheimer’s Disease, Malpetti M, Kievit RA, Passamonti L, Jones PS, Tsvetanov KA, Rittman T, Mak E, Nicastro N, Bevan-Jones WR, Su L, Hong YT, Fryer TD, Aigbirhio FI, O’Brien JT and Rowe JB, Brain, 143(5):1588-1602. (2020)
- Autosomal Dominantly Inherited Alzheimer Disease: Analysis of genetic subgroups by Machine Learning, Castillo-Barnes D, Su L, Ramrez J, Salas-Gonzalez D, Martinez-Murcia FJ, Illan IA, Segovia F, Ortiz A, Cruchaga C, Farlow MR, Xiong C, Graff-Radford NR, Schofield PR, Masters CL, Salloway S, Jucker M, Mori H, Levin J, Gorriz JM, Information Fusion, 58: 153-167. (2020)
- Early Microglial Activation and Peripheral Inflammation in Dementia with Lewy Bodies. Surendranathan A, Su L, Mak E, Passamonti L, Hong YT, Arnold R, Vázquez Rodríguez P, Bevan-Jones WR, Brain SAE, Fryer TD, Aigbirhio FI, Rowe JB, O’Brien JT , Brain, 141(12): 3415-3427. (2018)
- Cerebral small vessel disease in middle age and genetic predisposition to late-onset Alzheimer’s Disease, Stefaniak JD, Su L, Mak E, Bahaei NS, Wells K, Ritchie K, Waldman A, Ritchie CW, O’Brien JT, Alzheimer’s & Dementia, 14(2): 253-258. (2018)
- The midlife cognitive profiles of adults at high risk of late-onset Alzheimer’s disease: The PREVENT study, Ritchie K, Carriere K, Su L, O’Brien JT, Lovestone S, Wells K, Richie CW, Alzheimer’s & Dementia, 13(10): 1089-1097. (2017)
- [18F]AV-1451 Positron Emission Tomography in Alzheimer’s Disease and Progressive Supranuclear Palsy, Passamonti L, Vázquez Rodríguez P, Hong YT, Allinson KSJ, Williamson D, Borchert RJ, Sami S, Bevan-Jones WR, Jones SP, Arnold R, Surendranathan A, Mak E, Su L, Fryer TD, Aigbirhio FI, O’Brien JT, Rowe JB , Brain, 140(3): 781-791. (2017)
- Baseline and longitudinal grey matter changes in newly diagnosed Parkinson’s disease: ICICLE-PD study, Mak E, Su L, Williams GB, Firbank MJ, Lawson RA, Yarnall AJ, Duncan GW, Owen AM, Khoo TK, Brooks DJ, Rowe JB, Barker R, Burn DJ, O’Brien JT, Brain, 138(10): 2974-86. (2015)
Select awards
- 2017, Alzheimer’s Research UK Senior Research Fellowship
- 2016, International Psychogeriatric Association Junior Research Awards in Psychogeriatrics
- 2015, International College of Geriatric Psychoneuropharmacology Junior Investigator Award
